When California girl Susan Murphy is unwittingly clobbered by a meteor full of outer space gunk on her wedding day, she mysteriously grows to 49-feet-11-inches tall. The military jumps into action and Susan is captured and put into a secret government compound. There, she is renamed Ginormica and held along with a ragtag group of Monsters: the brilliant but insect-headed Dr. Cockroach, Ph.D.; the macho half-ape, half-fish, The Missing Link; the gelatinous and indestructible B.O.B.; and the 350-foot grub called Insectosaurus. Their confinement is cut short, however, when a mysterious alien robot lands on Earth and begins storming the country. In a moment of desperation, The President is persuaded to enlist the motley crew of Monsters to combat the alien robot and save the world from imminent destruction.
Cast: Reese Witherspoon, Seth Rogen, Hugh Laurie, Will Arnett, Kiefer Sutherland, Rainn Wilson, Stephen Colbert, Paul Rudd, Julie White, Jeffrey Tambor, Amy Poehler, Ed Helms, Renee Zellweger, John Krasinski and Sean Bishop